Dr. Hong Yu | Bacterial Infection | Best Researcher Award

Research Associate Professor at Medical University of South Carolina, United States

Dr. Hong Yu, M.D., is a distinguished Research Associate Professor at the Medical University of South Carolina (MUSC), specializing in biomedical and community health sciences. With a solid foundation in pathology and translational research, Dr. Yu has contributed significantly to understanding inflammatory diseases, bone regeneration, and immune signaling in oral health. Her research has garnered major NIH funding and has been published in high-impact journals. As a dedicated academician, Dr. Yu mentors emerging scholars and plays an active role in editorial services, scientific societies, and university committees. Her leadership roles at MUSC, including Director and Co-Director of key lab facilities, underscore her commitment to advancing scientific infrastructure. Recognized for her collaborative spirit and scientific rigor, Dr. Yu continues to drive innovation in aging, oral immunology, and metabolic disease research, positively impacting both clinical and research communities.

Professional Profile

ORCID

Education

Dr. Yu earned her M.D. degree from Beijing Medical University (1990–1994), followed by a pathology residency at the People’s Hospital of the same university (1990–1995). She further expanded her international exposure as an Ivu Wu Fellow at Queen Mary Hospital, University of Hong Kong (1998–1999). Her postdoctoral research trajectory in the United States included appointments at the Medical University of South Carolina in the Departments of Microbiology & Immunology, Pediatrics, and Oral Health Sciences (2000–2009). These formative years established her expertise in immunology, oral pathology, and translational biomedical research. With training spanning clinical practice and laboratory research, Dr. Yu possesses a rare combination of medical insight and bench-side innovation, enabling her to explore disease mechanisms and develop novel therapeutic approaches.

Work Experience

Dr. Yu’s career spans clinical, research, and academic leadership roles. Clinically, she served as a Resident and later an Attending Physician in Pathology at the People’s Hospital in Beijing (1990–2000). Transitioning to research, she held multiple postdoctoral positions at MUSC (2000–2009). She was appointed Research Assistant Professor (2011–2017) and subsequently Research Associate Professor in the Department of Oral Health Sciences (2017–2023). Since 2023, she has served as Research Associate Professor in the Department of Biomedical and Community Health Sciences. Her administrative contributions include leading preclinical and laboratory cores within the Center for Oral Health Research. As an educator, she teaches dental biochemistry and mentors pre-doctoral and summer students. Her multifaceted experience showcases her versatility in medical science, mentoring, and institutional development.

🏆 Awards & Honors

Dr. Yu has earned multiple NIH grants, including prestigious R21 and R01 awards for studies on periodontitis, immune signaling, and aging. Her Principal Investigator roles reflect her leadership in advancing oral and systemic health. She received internal honors like the Center for Healthy Aging Pilot Grant and was trusted with co-investigator duties on high-budget collaborative research. She has been invited to serve on the Editorial Review Boards of journals such as Cells, Journal of Dentistry and Oral Biology, and others, recognizing her expert insights. She also actively serves as a peer reviewer for more than 15 top-tier journals including Scientific Reports and Journal of Dental Research. Her selection as a judge at several MUSC research events underscores her status as a thought leader in her field.

Research Focus

Dr. Yu’s research centers on immune signaling in oral and systemic inflammatory diseases, with emphasis on sphingosine-1-phosphate receptors, CD38 signaling, and bone metabolism. Her work dissects the complex molecular pathways influencing osteoblastogenesis, osteoclastogenesis, and cytokine regulation, especially in conditions like periodontitis, metabolic syndrome, and aging. Her studies integrate oral microbiology, lipid signaling, and immunopathology to develop novel therapeutic interventions for bone regeneration and chronic oral infections. Through animal models and molecular biology tools, she investigates how systemic conditions exacerbate oral diseases, laying the foundation for cross-disciplinary treatment strategies. As a co-investigator on siRNA delivery systems for oral cancer, her focus also extends to molecular therapy and nanocarrier systems. Dr. Yu’s translational science approach bridges basic science and clinical applications, improving outcomes in oral and systemic health.

Conclusion

Dr. Hong Yu is highly suitable for the Research for Best Researcher Award. Her portfolio reflects the hallmarks of a top-tier scientist: sustained research productivity, leadership in biomedical science, mentorship, and service to the academic community. Her future-facing projects on immune responses in aging and chronic diseases showcase not only scientific excellence but also critical relevance to public health. Recognition through this award would not only honor her past contributions but encourage the continued evolution of her impactful research.

Publications to Noted

CD38 Inhibitor 78c Attenuates Pro‑Inflammatory Cytokine Expression and Osteoclastogenesis in Macrophages
Authors: William Lory; Nityananda Chowdhury, PhD; Bridgette Wellslager; Subramanya Pandruvada; Yan Huang; Özlem Yilmaz; Hong Yu
Journal: Cells
Year: 2024 (Nov)

GPR40/GPR120 Agonist GW9508 Improves Metabolic Syndrome‑Exacerbated Periodontitis in Mice
Authors: Yanchun Li; Hong Yu; Maria F. Lopes-Virella; Yan Huang
Journal: International Journal of Molecular Sciences
Year: 2024 (Sep)

The Presence of Periodontitis Exacerbates Non‑Alcoholic Fatty Liver Disease via Sphingolipid Metabolism‑Associated Insulin Resistance and Hepatic Inflammation in Mice with Metabolic Syndrome
Authors: Zhongyang Lu; Yanchun Li; Nityananda Chowdhury, PhD; Hong Yu; Wing-Kin Syn; Maria Lopes-Virella; Özlem Yilmaz; Yan Huang
Journal: International Journal of Molecular Sciences
Year: 2023 (May)

Inhibition of Sphingosine‑1‑Phosphate Receptor 2 by JTE013 Enhanced Alveolar Bone Regeneration by Promoting Angiogenesis
Authors: William Lory; Bridgette Wellslager; Chao Sun; Özlem Yilmaz; Hong Yu
Journal: International Journal of Molecular Sciences
Year: 2023 (Feb)

Inhibition of Sphingosine‑1‑Phosphate Receptor 2 by JTE013 Promoted Osteogenesis via Vesicle Trafficking, Wnt/Ca²⁺, and BMP/Smad Signaling
Authors: Simon Lin; Subramanya Pandruvada; Hong Yu
Journal: International Journal of Molecular Sciences
Year: 2021 (Nov)

Targeting S1PRs as a Therapeutic Strategy for Inflammatory Bone Loss Diseases—Beyond Regulating S1P Signaling
Author: Hong Yu
Journal: International Journal of Molecular Sciences
Year: 2021 (Apr)

Sphingosine‑1‑Phosphate Receptor 2 Controls Podosome Components Induced by RANKL Affecting Osteoclastogenesis and Bone Resorption
Authors: Li‑Chien Hsu; Sakamuri V. Reddy; Özlem Yilmaz; Hong Yu
Journal: Cells
Year: 2019 (Jan)

Prof. Dr. Esmail M. El-Fakharany | Antiviral | Best Researcher Award

Researcher at city of scientific research and technological applications, Egypt

Prof. Dr. Esmail Mohammed El-Fakharany is a distinguished Egyptian scientist in microbiology and biotechnology, currently serving as Professor in the Protein Research Department at the Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications. With a career dedicated to exploring the therapeutic applications of natural and recombinant proteins, he has made significant contributions in antiviral and anticancer research. Dr. El-Fakharany has published extensively in high-impact journals, including Scientific Reports – Nature, and has authored multiple book chapters. He is also an active mentor for MSc and Ph.D. students, a regular contributor to international conferences, and a patent innovator with numerous submissions to the Egyptian Patent Office. His research and mentorship have impacted various fields, including biotechnology, immunology, and molecular biology. Through teaching, research, and public engagement, he continues to foster innovation and scientific excellence both nationally and internationally. 🧬📚🦠

professional profile

Scopus Profile

ORCID

Education

Dr. El-Fakharany earned his Ph.D. in Microbiology with a minor in Biotechnology in 2012 from Al-Azhar University, Cairo. His doctoral thesis explored the antiviral activity of natural and recombinant lactoferrin, laying the foundation for his lifelong interest in therapeutic proteins. Prior to that, he completed an M.Sc. in Microbiology in 2009 at the same institution, with a focus on antiviral agents derived from microbial and natural sources. He also holds a Diploma in Public Health (Microbiology) from the High Institute of Public Health, Alexandria University (2006), and graduated with distinction in B.Sc. Microbiology from Al-Azhar University in 2003. His education reflects a strong interdisciplinary grounding in microbiology, biotechnology, and public health, preparing him to tackle challenges in drug development, protein engineering, and infection control. 📘🧫🎓

Work Experience

With over 20 years of research and teaching experience, Prof. El-Fakharany has held multiple academic and research roles culminating in his current position as Professor of Protein Research. His expertise includes therapeutic protein purification, immunoblotting, molecular biology, antiviral assays, and cell culture. He has played a pivotal role in training students across various disciplines including pharmacy, agriculture, and biotechnology, and has mentored numerous graduate theses. His experience also extends to managing scientific projects and participating in collaborative research initiatives. He regularly contributes to workshops, conferences, and summer schools, sharing his knowledge with local and international peers. He also actively contributes to training programs for visiting students and early-career researchers. As a result, Dr. El-Fakharany is recognized not only as a prolific scientist but also as a respected academic leader and mentor. 🧪👨‍🏫🔬

Research Focus

Dr. El-Fakharany’s research centers on the isolation, characterization, and therapeutic application of natural and recombinant proteins, particularly lactoferrin. His groundbreaking studies explore how these proteins can be harnessed as antiviral and anticancer agents, often using molecular biology and immunology tools to evaluate efficacy. He has specialized in using biotechnological methods to discover novel antiviral agents derived from microorganisms and other bioresources. His work also investigates cellular and molecular mechanisms underlying pathogen-host interactions, tumor progression, and immune responses. By integrating protein biochemistry with microbiology and tissue culture techniques, his research offers valuable insights for drug development, vaccine design, and therapeutic innovation. With a multidisciplinary approach that blends microbiology, molecular genetics, and bioengineering, Dr. El-Fakharany’s contributions aim to improve public health outcomes through novel biotherapeutics. 🧫💉🔍

Conclusion

Prof. Esmail Mohammed El-Fakharany is highly suitable for the Research for Best Researcher Award. His extensive experience, significant scientific contributions, dedication to innovation, and active mentorship align closely with the award’s objectives. With further emphasis on international collaboration and translational commercialization, he stands out as a strong and deserving candidate. 🏆🧪🌍

Publications to Noted

Title: Persulphate activation by ferrous sulphate for tertiary treatment of real domestic wastewater to meet the standards of irrigating food crops
Authors: Mohamed Fouad, Esmail M. El-Fakharany, Mohamed Mossad, Mahmoud Samy, Mohamed Gar Alalm
Journal: Journal of Water Process Engineering
Citations: 0
Year: 2025

Title: A novel nanocomposite fabrication of chitosan with tungstate oxide nanoplatform doped with bovine lactoperoxidase: characterizations and diverse biological assessments
Authors: Esmail M. El-Fakharany, Hamada El-Gendi, Mohamed H. El-Sayed, Mahmoud A. Abdelaziz, Ahmed I. Abd-Elhamid
Journal: Biomass Conversion and Biorefinery
Citations: 1
Year: 2025

Title: Metal-organic framework MIL-101(Fe) functionalized with folic acid as a multifunctional nanocarrier for targeted chemotherapy-photodynamic therapy
Authors: Eman Serag, Esmail M. El-Fakharany, Sherif F. Hammad, Mohamed E. El-Khouly
Journal: Biomaterials Science
Citations: 0
Year: 2025

Title: Chemopreventive effect of Pistacia vera leaf extract against mammary carcinoma induced by dimethyl-benz(a)anthracene in vivo and in vitro
Authors: Ali Gaithan Alkhathami, Esmail M. El-Fakharany, Mohamed H. El-Sayed, Hussam Askar, Mahmoud Ashry
Journal: Food and Chemical Toxicology
Citations: 4
Year: 2025

Title: Statistical optimization of hyaluronidase production by Ochrobactrum intermedium MEFS strain along with in vivo application in the treatment of aesthetic filler complications
Authors: Fafy A. Mohammed, Mai A. Ebraheem, Esmail M. El-Fakharany, Sherif Moussa Husseiny
Journal: International Journal of Biological Macromolecules
Citations: 0
Year: 2025

Title: Fabrication and characterization of lactoperoxidase coated the modified graphene oxide-based nanocomposite for medical applications
Authors: Abdelaziz A. Nayl, Esmail M. El-Fakharany, Ahmed I. Abd-Elhamid, Ashraf A. Aly, Stefan J. Bräse
Journal: International Journal of Biological Macromolecules
Citations: 0
Year: 2025

Title: Corrigendum to “Comprehensive insight into recent algal enzymes production and purification advances: Toward effective commercial applications: A review”
Authors: Esmail M. El-Fakharany, Ahmed K. Saleh, Yousra A. El-Maradny, Wafa Mazi, Hamada El-Gendi
Journal: International Journal of Biological Macromolecules
Citations: 0
Year: 2024

Hong Yu | Bacterial Infection | Best Researcher Award

Dr. Hong Yu | Bacterial Infection | Best Researcher Award

Professional Profile

Education

Work Experience

🏆 Awards & Honors

Research Focus

Conclusion

Publications to Noted

Esmail M. El-Fakharany | Antiviral | Best Researcher Award

Prof. Dr. Esmail M. El-Fakharany | Antiviral | Best Researcher Award

professional profile

Education

Work Experience

Research Focus

Conclusion

Publications to Noted

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