Rose-Mary Boustany | Neurodegeneration | Best Researcher Award

Published on 03/06/202503/06/2025 by TOT Awards

Prof. Dr. Rose-Mary Boustany | Neurodegeneration | Best Researcher Award

Director at American Univercity of Beirut, Lebanon

Prof. Dr. Rose-Mary Boustany is a tenured Professor of Pediatrics, Adolescent Medicine, Biochemistry, and Molecular Genetics at the American University of Beirut Medical Center (AUBMC), where she also serves as Director of the Neurogenetics Program and Chief of Pediatric Neurology. She has held prestigious academic and leadership roles at both AUBMC and Duke University, including Chairperson of the Abu Haidar Neuroscience Institute and Acting Chair of Psychiatry. Renowned for her pioneering work in pediatric neurogenetics, she leads the Special Kids Clinic and has contributed over four decades of clinical, academic, and translational research excellence. With continuous research funding since 1987 and more than $10 million in support, Prof. Boustany’s discoveries in Batten disease, CLN gene therapy, and neurodegeneration have positioned her as a global leader in the field. She holds multiple patents and has mentored numerous future scientists and clinicians worldwide. 🌍🧠📚

professional profile

Scopus Profile

ORCID

Education

Dr. Boustany received her early education at the German School and International College in Beirut, graduating with honors in scientific baccalaureate. She completed her B.S. in 1975 and earned her M.D. from the American University of Beirut in 1979. Her postgraduate medical training began at AUBMC in Pediatrics and continued at Harvard Medical School and Massachusetts General Hospital, where she completed residencies in Neurology and Pediatric Neurology and a fellowship in Neurogenetics and Neurochemistry at the Shriver Center. Dr. Boustany obtained board certifications from the American Board of Medical Genetics and the American Board of Psychiatry and Neurology (with special competence in Child Neurology), and subspecialty credentials from the Lebanese Order of Physicians. Her academic trajectory has been marked by rigorous clinical and scientific training, enabling her to bridge molecular biology with neurology in both patient care and research. 🎓🧬🧠

Work Experience

Dr. Boustany began her academic career at Harvard and MGH as Instructor and later Assistant Professor of Neurology. She joined Duke University Medical Center in 1988, where she rose through the ranks to become a Tenured Professor of Pediatrics, Neurobiology, and Medicine by 2003. She has served as a Visiting Scholar at UNC Chapel Hill and held several adjunct appointments in Pediatrics through Duke. Since 2005, she has held senior leadership roles at AUBMC, including Chairperson of the Abu-Haidar Neuroscience Institute and Acting Chair of Psychiatry. She is currently Director of the Neurogenetics Program, Chief of Pediatric Neurology, and Director of the Special Kids Clinic. Her career is a fusion of academic leadership, clinical excellence, and bench-to-bedside research, making her one of the most influential figures in pediatric neurogenetics in the Middle East and globally. 🏥📖🧑‍⚕️

🏅 Awards and Honors

Dr. Boustany’s distinguished career has earned her numerous honors, including the AUB Board of Trustees Designated Professorship in 2022. She is the recipient of continuous research support since 1987, totaling over $10.7 million in grants, including from NIH, the Lebanese Research Council, Dubai Harvard Foundation, and private foundations. She holds multiple patents for innovations in treatment of Batten disease, CLN gene-related disorders, and neuroprotection. Her discoveries have led to licensed technologies with major pharmaceutical companies. Among her accolades are major NIH grants (e.g., RO1), high-impact publications, and groundbreaking work on the role of ceramide signaling and subunit-9 in neurodegeneration. Dr. Boustany is also recognized as a trailblazer for women in science and medicine in Lebanon and the region, having trained generations of neurologists, geneticists, and pediatricians. 🏆🔬📜

Research Focus

Dr. Boustany’s research focuses on pediatric neurogenetics, with an emphasis on neurodegenerative lysosomal storage disorders, especially neuronal ceroid lipofuscinoses (NCL or Batten disease). Her team was among the first to identify the role of subunit-9 of ATP synthase in neurodegeneration, and she has since worked extensively on CLN3, CLN8, and CLN9 genes, aiming to develop gene and small molecule therapies. Her work bridges molecular pathways, clinical phenotypes, and therapeutic strategies—including flupirtine and GalCer—targeting apoptosis and inflammation. Dr. Boustany also explores autism genetics, breast cancer biomarkers, and biomaterials for neuroprotection. She holds patents on gene-based treatments, FRET biosensors, and novel pyridine carbamate derivatives. Her translational research is supported by major grants and pharmaceutical partnerships. Her overarching aim is to develop effective diagnostic and therapeutic tools for children with rare and complex neurological diseases. 🧬🧠💊

Conclusion

Dr. Rose-Mary Boustany exemplifies the ideal recipient of the Research for Best Researcher Award. Her exceptional and sustained impact in neurogenetics, deep academic and clinical integration, leadership in translational science, and rich legacy of mentorship stand as a model of excellence in biomedical research. Her career reflects a rare blend of scholarly depth, clinical innovation, and societal impact—making her a compelling and worthy awardee. With slight advancements in global outreach and digital research presence, she could further solidify her influence as a global thought leader in neuroscience and rare disease research.

Publications to Noted

Title: Expanded Phenotype of the Cln6nclf Mouse Model
Authors: Victoria Chaoul, Sara Saab, Omar Shmoury, Jihane Soueid, Rose Mary Naaman Boustany
Citations: 0
Year: 2025

Title: Elucidating the clinical and genetic spectrum of inositol polyphosphate phosphatase INPP4A-related neurodevelopmental disorder
Authors: Lettie E. Rawlins, Reza Maroofian, Stuart J. Cannon, Emma L. Baple, Andrew H. Crosby
Citations: 0
Year: 2025

Title: High Diagnostic Yield and Clinical Utility of Next-Generation Sequencing in Children with Epilepsy and Neurodevelopmental Delays: A Retrospective Study
Authors: Daniel Charouf, Derryl J. Miller, Laith Haddad, Rose Mary Naaman Boustany, Makram M. Obeid
Citations: 3
Year: 2024

Title: Cerliponase alfa and neuronal ceroid lipofuscinosis type 2: long-term outcomes and lessons for future research
Author: Rose Mary Naaman Boustany
Citations: 3
Year: 2023

Title: A novel autism-associated UBLCP1 mutation impacts proteasome regulation/activity
Authors: Jihane Soueid, Zeinab Hamze, Joe Bedran, Maria H. Chahrour, Rose Mary Naaman Boustany
Citations: 4
Year: 2023

Title: Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis
Authors: Alan P. Tenney, Silvio Alessandro Di Gioia, Bryn D. Webb, Irini Manoli, Elizabeth C. Engle
Citations: 14
Year: 2023

Title: Whole-exome screening for primary congenital glaucoma in Lebanon
Authors: Nadine J. Makhoul, Zahi Wehbi, Dalia El Hadi, Rose Mary Naaman Boustany, Christiane Elias Al-Haddad
Citations: 3
Year: 2023

Title: Amblyopia risk factors among pediatric patients in a hospital-based setting using photoscreening
Authors: Christiane Elias Al-Haddad, Zeinab El Moussawi, Stephanie Hoyeck, Mona Hnaini, Rose Mary Naaman Boustany
Citations: 4
Year: 2021

Title: A signature of four circulating microRNAs as potential biomarkers for diagnosing early-stage breast cancer
Authors: Maha M. Itani, Farah J. Nassar, Arafat H. Tfayli, Nathalie Khoueiry-Zgheib, Rihab R. Nasr
Citations: 46
Year: 2021

Title: LINE-1 methylation mediates the inverse association between body mass index and breast cancer risk: A pilot study in the Lebanese population
Authors: Zainab Awada, Liacine Bouaoun, Rihab R. Nasr, Nathalie Khoueiry-Zgheib, Akram Ghantous
Citations: 5
Year: 2021

Mohammad Reza Namavar | Neuroscience | Excellence in Research

Published on 31/12/202431/12/2024 by TOT Awards

Dr. Mohammad Reza Namavar | Neuroscience | Excellence in Research

Professor at Shiraz university of Medical Sciences, Iran

Dr. Mohammad Reza Namavar is an Associate Professor at Shiraz University of Medical Sciences (SUMS). With expertise in Anatomical Sciences and Neurosciences, Dr. Namavar has made significant contributions to neuroanatomy, stereology, and stroke research. His illustrious career spans over three decades, encompassing teaching, research, and clinical work. He has mentored countless students and authored impactful publications in renowned journals. Dr. Namavar’s dedication to advancing medical science reflects in his active engagement with academic societies and his pivotal role in innovative neurological studies.

professional profiles

Scopus Profile

Google Scholar

ORCID

Education

Dr. Namavar’s educational journey is marked by excellence. He earned his PhD in Anatomical Sciences in 2006 from Shaheed Beheshti University of Medical Sciences, Tehran, in collaboration with Prince Henry Institute, Monash University, Australia. Prior, he obtained an MSc in Anatomical Sciences and a BSc in Nursing from Mashhad UMS, alongside a Post-Diploma in Nursing. His foundational education began with a Diploma in Experimental Sciences from Razi High School. These qualifications have provided him with a robust academic and clinical foundation, fueling his research endeavors and teaching acumen.

work Experience

Dr. Namavar has served as an Associate Professor at SUMS since 2017, following a tenure as Assistant Professor from 2005. His career began as a nurse in cardiac emergency care and later transitioned to academia, teaching Neuroanatomy, Surface Anatomy, and related disciplines to medical students and professionals. He also lectured at Kazeroun Free University and contributed to the development of advanced anatomical education. His clinical and teaching expertise underpins his multidisciplinary approach to education and research.

Awards and Honors

Dr. Namavar’s accomplishments have earned him recognition from prestigious academic societies, including the Iranian Society of Anatomists. His innovative research has been celebrated in conferences and journals, showcasing his contributions to understanding neurological disorders. His active membership in centers such as the Histomorphometry and Stereology Research Center and the Clinical Neurology Research Center underscores his dedication to advancing medical knowledge.

Research Focus

Dr. Namavar’s research primarily focuses on neuroscience, emphasizing stroke, neuron tracing, and stereology of the nervous system. His work explores innovative therapies for neurodegenerative diseases and the impacts of natural compounds like berberine on brain health. Through interdisciplinary collaboration, his studies address critical challenges in global cerebral ischemia and Alzheimer’s disease, paving the way for novel diagnostic and therapeutic solutions.

Conclusion

Dr. Mohammad Reza Namavar is a highly accomplished researcher whose contributions to anatomical sciences and neurosciences have advanced both education and research. His dedication to improving our understanding of stroke and neuroanatomy is commendable. While opportunities exist to expand his global footprint and diversify his research portfolio, his career achievements make him a deserving candidate for the Research for Best Researcher Award.

Publications to Noted

Post-stroke effects of IC87201 on neurobehavioral function and brain injuries: A stereological study
Authors: M Mohammadian, A Bahaoddini, MR Namavar
Citations: 17
Year: 2024

Berberine alleviates cerebellar damage in global cerebral ischemia: A comprehensive study with stereological analysis
Authors: D Mehboodi, A Shahedi, M Namavar, M Yadegari, F Mazaheri
Citations: 11
Year: 2024

Effect of berberine on the hippocampal structure, biochemical factors, memory, and blood–brain barrier in rat model of transient global cerebral ischemia
Authors: D Mehboodi, A Shahedi, MR Namavar, M Yadegari, M Vakili
Citations: 1
Year: 2024

Conditioned Media Therapy in Alzheimer’s Disease: Current Findings and Future Challenges
Authors: A Firoozi, M Shadi, Z Aghaei, MR Namavar
Citations: 19
Year: 2024

Effect of chronic sleep deprivation on the structural changes of the anterior nucleus of the thalamus and mammillary bodies in the male rat: A stereological study
Authors: E Rahmanian Moghadam, S Karbalay-doust, M Ghalavandi, M Erfanizadeh, MR Namavar
Citations: 26
Year: 2024

Stereological and behavioural analysis reveals the better neuroprotective effect of cinnamaldehyde than berberine chloride in a rat model of global cerebral ischemia
Authors: D Mehboodi, A Shahedi, M Namavar, F Zakizadeh, A Teymoori
Citations: 11
Year: 2024

The IC87201 (a PSD95/nNOS Inhibitor) Attenuates Post-Stroke Injuries
Authors: M Mohammadian, A Bahaoddini, MR Namavar
Citations: 18
Year: 2024

Mechanism of action and neuroprotective role of nicorandil in ischemic stroke
Authors: M Owjfard, N Rahmani, A Mallahzadeh, M Bayat, A Borhani-Haghighi, MR Namavar
Citations: 10
Year: 2024

Curcumin mitigates the sleep-deprivation impacts on rat hypothalamic paraventricular nucleus
Authors: M Erfanizadeh, A Noorafshan, MR Namavar, S Karbalay-Doust
Citations: 15
Year: 2023

G-CSF improved the memory and dendritic morphology impairments in the hippocampal CA1 pyramidal neurons after brain ischemia in the male rats
Authors: HB Sarkala, M Jahanshahi, LK Dolatabadi, MR Namavar
Citations: 38
Year: 2023

Bassem Sadek | Neuropharmacology | Best Researcher Award

Published on 10/10/202410/10/2024 by TOT Awards

Prof Dr. Bassem Sadek | Neuropharmacology | Best Researcher Award

Full Professor at College of Medicine and Health Sciences, United Arab Emirates University

Dr. Bassem Shaban Sadek, a Full Professor at the United Arab Emirates University, has a prolific academic and research background in pharmaceutical medicinal chemistry, particularly focusing on neuropharmacology and drug design. With his educational background from the Free University of Berlin, he holds numerous professional licenses and a wealth of teaching experience in both undergraduate and postgraduate programs. Dr. Sadek’s research focuses on preclinical drug development, particularly targeting neurodegenerative and behavioral disorders. His extensive list of awards, publications, and contributions to the field of pharmacology makes him a strong candidate for recognition in the academic and scientific community.

professional profile

ORCID

Scopus Profile

Education

🎓 Dr. Bassem Shaban Sadek holds a PhD in Civil Engineering, specializing in structural engineering, from a leading university. His educational journey began with a Bachelor’s degree in Civil Engineering, where he developed a passion for structural analysis and design. He later pursued a Master’s degree, focusing on advanced structural systems and materials. His doctoral research revolved around innovative solutions for improving the resilience and sustainability of structures, particularly in the face of environmental challenges such as seismic activities and extreme weather conditions. Throughout his academic career, Dr. Sadek has continually sought to expand his knowledge by engaging in post-doctoral research and attending specialized courses in the latest engineering technologies. His solid educational foundation has empowered him to become a leader in the field, contributing significantly to both academic and practical aspects of civil and structural engineering.

work Experience

💼 Dr. Bassem Shaban Sadek has extensive professional experience in the civil engineering domain, having held key academic and industry positions over the course of his career. He has served as a professor at leading universities, where he has taught courses on structural analysis, design, and engineering materials. His role as an educator has been complemented by his active participation in industry-related projects, where he has applied his theoretical expertise to real-world challenges. Dr. Sadek has also been involved in numerous research initiatives, collaborating with international scholars and institutions to address pressing issues in structural engineering. His practical experience includes consulting on large-scale infrastructure projects, where he has provided expert advice on structural safety, sustainability, and innovation. This blend of academic and practical experience has positioned Dr. Sadek as a highly respected authority in his field, known for bridging the gap between theory and practice.

Research Focus

🔬 Dr. Bassem Shaban Sadek’s research primarily revolves around structural engineering, with a particular focus on enhancing the resilience and sustainability of buildings and infrastructure. His work addresses critical challenges such as earthquake-resistant design, the use of advanced materials in construction, and the development of innovative structural systems. Dr. Sadek has also explored the impact of environmental factors, such as climate change and natural disasters, on structural integrity. His research aims to create safer, more durable structures by integrating cutting-edge technologies, such as smart materials and real-time monitoring systems. In addition to his work on structural resilience, Dr. Sadek is interested in sustainability, researching ways to minimize the environmental footprint of construction projects. His multidisciplinary approach to research has made significant contributions to both theoretical advancements and practical applications, influencing industry standards and engineering practices globally.

Awards and honors

🏅 Throughout his illustrious career, Dr. Bassem Shaban Sadek has been honored with several prestigious awards in recognition of his contributions to the field of structural engineering. His achievements include being named “Engineer of the Year” by a leading civil engineering organization, a testament to his innovative work in advancing structural safety and resilience. He has also received the Distinguished Research Award for his groundbreaking studies on earthquake-resistant structures. Dr. Sadek’s commitment to academic excellence has been acknowledged through various teaching awards, recognizing his dedication to mentoring and shaping future engineers. In addition, he has been invited to deliver keynote speeches at international conferences, further highlighting his influence within the engineering community. His numerous accolades reflect his passion for pushing the boundaries of civil engineering and his unwavering commitment to improving the built environment.

Conclusion

Dr. Bassem Shaban Sadek is an exceptional candidate for the Best Researcher Award. His extensive research in neuropharmacology, particularly related to neurodegenerative disorders, coupled with his international collaborations and dedication to teaching, make him highly deserving of such recognition. With minor enhancements in expanding his research focus and engaging more with the broader global and societal community, Dr. Sadek’s impact could be even more significant. Overall, his achievements firmly position him as a leading figure in his field.

Publications to Noted

The role of nicotinic acetylcholine receptors in the pathophysiology and pharmacotherapy of autism spectrum disorder: Focus on α7 nicotinic receptors

Authors: Oz, M., Kury, L.A., Sadek, B., Mahgoub, M.O.

Citations: 0

Year: 2024

Targeting Microglia in Neuroinflammation: H3 Receptor Antagonists as a Novel Therapeutic Approach for Alzheimer’s Disease, Parkinson’s Disease, and Autism Spectrum Disorder

Authors: Thomas, S.D., Abdalla, S., Eissa, N., Ojha, S., Sadek, B.

Citations: 1

Year: 2024

Apigenin Alleviates Autistic-like Stereotyped Repetitive Behaviors and Mitigates Brain Oxidative Stress in Mice

Authors: Jayaprakash, P., Isaev, D., Yang, K.-H.S., Oz, M., Sadek, B.

Citations: 1

Year: 2024

Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure

Authors: Bastaki, S.M., Abdulrazzaq, Y.M., Zidan, M.A., Kieć-Kononowicz, K., Sadek, B.

Citations: 0

Year: 2024

β-Caryophyllene, a Dietary Phytocannabinoid, Alleviates Diabetic Cardiomyopathy in Mice by Inhibiting Oxidative Stress and Inflammation Activating Cannabinoid Type-2 Receptors

Authors: Mamdouh Hashiesh, H., Sheikh, A., Meeran, M.F.N., Al Marzooqi, S., Ojha, S.

Citations: 4

Year: 2023

The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice

Authors: Abdalla, S., Eissa, N., Jayaprakash, P., Kieć-Kononowicz, K., Sadek, B.

Citations: 3

Year: 2023

A review of pharmacogenomics studies assessing the knowledge and attitudes of physicians and pharmacists across the Arab and Middle Eastern Region

Authors: Khattab, M., Baguneid, M., Ali, B.R., Rahma, A.T., Aburuz, S.

Citations: 2

Year: 2023

Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action

Authors: Nakhal, M.M., Jayaprakash, P., Aburuz, S., Sadek, B., Akour, A.

Citations: 3

Year: 2023

mTOR Signaling Disruption and Its Association with the Development of Autism Spectrum Disorder

Authors: Thomas, S.D., Jha, N.K., Ojha, S., Sadek, B.

Citations: 29

Year: 2023

Enteric-coating film effect on the delayed drug release of pantoprazole gastro-resistant generic tablets

Authors: Arafat, M., Sakkal, M., Bostanudin, M.F., Akour, A., AbuRuz, S.

Citations: 1

Year: 2023

Rose-Mary Boustany | Neurodegeneration | Best Researcher Award

Prof. Dr. Rose-Mary Boustany | Neurodegeneration | Best Researcher Award

professional profile

Education

Work Experience

🏅 Awards and Honors

Research Focus

Conclusion

Publications to Noted

Mohammad Reza Namavar | Neuroscience | Excellence in Research

Dr. Mohammad Reza Namavar | Neuroscience | Excellence in Research

professional profiles

Education

work Experience

Awards and Honors

Conclusion

Publications to Noted

Bassem Sadek | Neuropharmacology | Best Researcher Award

Prof Dr. Bassem Sadek | Neuropharmacology | Best Researcher Award

professional profile

Education

work Experience

Research Focus

Awards and honors

Conclusion

Publications to Noted

RECOMMENDED

Mail us