Posted on by sciencefather
70 / 100
Powered by Rank Math SEO
SEO Score

Dr. Barry Cooperman | Biological Chemistry | Best Researcher Award

Professor at University of Pennsylvania, United States

Barry S. Cooperman is a distinguished chemist known for his extensive contributions to enzymology and biochemical research. Born in Brooklyn, New York, in 1941, he pursued an illustrious academic and professional career at top institutions, including Columbia University, Harvard University, and the Pasteur Institute. His research has focused on enzymatic mechanisms, ribosome function, and antibiotic resistance. As a Professor of Chemistry at the University of Pennsylvania, he has held numerous leadership roles, including Vice Provost for Research and Director of the French Institute for Culture and Technology. His work has earned him prestigious awards such as the Chevalier de l’Ordre des Palmes Académiques from the French Government and election as a Fellow of the American Association for the Advancement of Science. He has also contributed to groundbreaking patents in biochemical technology.

professional profile

Google Scholar

Scopus Profile

Educational Details

Barry S. Cooperman’s academic journey began at Columbia College, where he earned a Bachelor of Arts degree in 1962, graduating Magna cum laude and being inducted into Phi Beta Kappa. He continued his studies at Harvard University, obtaining a Ph.D. in Chemistry in 1968. His doctoral research laid the groundwork for his later work in enzymology and nucleic acid chemistry. He then pursued postdoctoral training at the prestigious Pasteur Institute in Paris from 1967 to 1968, where he expanded his expertise in molecular biochemistry. His educational background, combined with rigorous research, enabled him to contribute significantly to various biochemical and enzymatic studies. His international exposure and extensive training have been instrumental in shaping his approach to scientific research, mentoring, and academic leadership.

Professional Experiences

Barry S. Cooperman began his academic career as an Assistant Professor of Chemistry at the University of Pennsylvania in 1968. By 1972, he had advanced to Associate Professor and, in 1977, became a full Professor. Throughout his tenure, he played a crucial role in shaping biochemical education and research. He served as Co-Chairman and later Chairman of the Undergraduate Biochemistry Major from 1968 to 1982, and as Vice Provost for Research at the university from 1982 to 1995. His leadership extended beyond the university, serving on the Board of Trustees of Associated Universities Inc. and chairing the board from 1989 to 1991. He also contributed to numerous scientific and policy boards, including the Max Planck Institute for Molecular Genetics and the Wistar Institute. His editorial role at Biochimie from 2007 to 2014 further highlights his influence in the field of biochemical research.

Awards and Honors 🏆

Barry S. Cooperman’s contributions to science have been widely recognized through numerous awards and fellowships. As a graduate student, he was awarded predoctoral fellowships from the NIH and NSF (1962-67) and later a NATO postdoctoral fellowship at the Pasteur Institute (1967-68). His early academic career was marked by the Merck Faculty Award (1970) and a Sloan Foundation Award (1974-78). He later served on the Physical Biochemistry Study Section (1978-82), reflecting his deep involvement in research evaluation. In 2004, he was honored by the French Government with the title Chevalier de l’Ordre des Palmes Académiques for his contributions to education and research collaboration. That same year, he was elected as a Fellow of the American Association for the Advancement of Science. His recognition as the Zhu Kezhen Lecturer at Zhejiang University in China in 2005 further underscores his global impact on scientific research.

Research Interest:

Barry S. Cooperman’s research has revolved around the mechanisms of enzymatic catalysis, nucleic acid chemistry, and ribosome function. He has made significant contributions to understanding the role of metal ions in enzyme-catalyzed hydrolysis, a key process in biological systems. His studies on ribosomal translation have provided crucial insights into protein synthesis, which have implications for antibiotic development and genetic engineering. His work in nucleic acid enzymology has helped elucidate the biochemical pathways involved in DNA and RNA synthesis. Additionally, he has explored phosphate transfer reactions, contributing to advancements in drug targeting and molecular medicine. His interdisciplinary approach has bridged chemistry and biology, making his research valuable to fields such as biochemistry, molecular genetics, and pharmacology. His studies continue to influence the scientific community, shaping the development of novel therapeutic strategies.

Conclusion

Dr. Barry S. Cooperman is an outstanding candidate for the Best Researcher Award due to his extensive and impactful scientific contributions. His research, mentorship, and leadership roles have left a lasting mark on chemistry and biochemistry. While some areas could benefit from broader outreach, his legacy as a pioneering researcher is undeniable, making him highly deserving of recognition.

Publications to Noted:

A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs

Authors: RW Wagner, JE Smith, BS Cooperman, K Nishikura

Citations: 423

Year: 1989

Evolutionary conservation of the active site of soluble inorganic pyrophosphatase

Authors: BS Cooperman, AA Baykov, R Lahti

Citations: 242

Year: 1992

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

Authors: A Wei, H Rubin, BS Cooperman, DW Christianson

Citations: 234

Year: 1994

Kinetically competent intermediates in the translocation step of protein synthesis

Authors: D Pan, SV Kirillov, BS Cooperman

Citations: 215

Year: 2007

Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins

Authors: H Rubin, ZM Wang, EB Nickbarg, S McLarney, N Naidoo, BS Cooperman

Citations: 214

Year: 1990

The structural basis for pyrophosphatase catalysis

Authors: P Heikinheimo, J Lehtonen, A Baykov, R Lahti, BS Cooperman

Citations: 177

Year: 1996

Dynamics of translation by single ribosomes through mRNA secondary structures

Authors: C Chen, H Zhang, SL Broitman, M Reiche, I Farrell, BS Cooperman

Citations: 172

Year: 2013

Photoincorporation of tetracycline into Escherichia coli ribosomes. Identification of the major proteins photolabeled by native tetracycline and tetracycline photoproducts and derivatives

Authors: RA Goldman, T Hasan, CC Hall, WA Strycharz, BS Cooperman

Citations: 171

Year: 1983

Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors

Authors: NM Schechter, JL Sprows, OL Schoenberger, GS Lazarus, BS Cooperman

Citations: 164

Year: 1989

Engine out of the chassis: cell-free protein synthesis and its uses

Authors: G Rosenblum, BS Cooperman

Citations: 155

Year: 2014

Barry Cooperman | Biological Chemistry | Best Researcher Award

You May Also Like