Dr. Ajoy kumar Bauri | Isolation | Best Researcher Award
Scientific Officer at Bhabha Atomic Research Centre, Trombay, Mumbai , India
Dr. Ajoy Kumar Bauri is a Senior Scientist (SO ‘F’) at the Bio-Organic Division, Bhabha Atomic Research Centre (BARC), Mumbai, Dr. Bauri’s primary research interests lie in the investigation of bioactive secondary metabolites from medicinal plants, marine organisms, and microorganisms. He is a specialist in isolating and characterizing natural products that serve as potential pharmaceutical agents. His work focuses on developing safer, more potent drugs from natural resources such as medicinal herbs and marine organisms, contributing significantly to the fields of pharmacology and biotechnology. Through his groundbreaking research, Dr. Bauri is advancing the development of novel agents with anti-cancer, anti-inflammatory, and anti-microbial properties, aiming to improve global healthcare.
professional profiles
Dr. Ajoy Kumar Bauri holds a Ph.D. in Science, specializing in the isolation and characterization of bioactive natural products, particularly secondary metabolites from medicinal plants and marine organisms. His educational background laid a strong foundation for his scientific career, enabling him to develop a deep understanding of bio-organic chemistry and pharmacology. His focus on medicinal plants, natural product chemistry, and molecular pharmacology stems from his academic pursuits, during which he gained expertise in advanced chromatographic techniques, spectroscopy, and the structural elucidation of bioactive compounds. He continuously strives to stay updated with the latest advancements in his field, ensuring his work remains at the cutting edge of bio-organic and pharmaceutical research.
work Experience
Dr. Ajoy Kumar Bauri has over three decades of research experience at Bhabha Atomic Research Centre (BARC), Mumbai. During his tenure, he has specialized in investigating bioactive secondary metabolites from traditional medicinal plants, marine organisms, and microorganisms. Dr. Bauri has extensive experience in utilizing advanced chromatographic techniques, including column chromatography, high-performance liquid chromatography, and thin-layer chromatography to isolate bioactive compounds. His expertise also extends to spectroscopic analysis, employing various techniques such as NMR, mass spectrometry, IR spectroscopy, and X-ray diffraction to elucidate the structures of isolated compounds. In addition to his laboratory work, Dr. Bauri has studied the potential biomedical applications of these compounds, including their anti-cancer, anti-ulcer, anti-inflammatory, and anti-microbial activities. He has also explored the biosynthetic and biotransformation processes of these compounds, using bacterial and fungal cultures to produce novel analogues for further study.
Awards and Honors
Dr. Ajoy Kumar Bauri’s contributions to the field of bioactive natural products have earned him recognition in various scientific circles. Although specific awards and honors are not detailed in the provided information, his work is widely acknowledged in the scientific community for its potential impact on pharmaceutical research. His focus on isolating bioactive compounds from natural sources and contributing to drug development, especially in the areas of anti-cancer, anti-inflammatory, and anti-microbial therapies, has made him a valuable member of the Bhabha Atomic Research Centre (BARC). He has also been instrumental in the exploration of marine organisms and microorganisms as sources of novel bioactive molecules. Dr. Bauri’s research continues to influence future drug development, and his scientific excellence makes him a candidate for recognition in national and international research awards in pharmaceutical science and bio-organic chemistry.
Research Focus
Dr. Ajoy Kumar Bauri’s primary research focus is on the investigation of bioactive secondary metabolites derived from medicinal plants, marine organisms, and microorganisms. He isolates and characterizes new pharmaceutical agents, especially those used in traditional herbal and Ayurvedic systems. Dr. Bauri’s work emphasizes the exploration of natural products as a safer and more potent alternative to synthetic drugs, focusing on their potential in treating diseases like cancer, infections, ulcers, and inflammation. His research spans the isolation of compounds using advanced chromatographic techniques, followed by detailed structural characterization through various spectroscopic methods such as NMR, mass spectrometry, and X-ray diffraction. Additionally, Dr. Bauri investigates the biosynthesis and biotransformation of these compounds to create novel analogues, contributing to the development of new, more effective therapeutics. His research is aimed at the biomedical applications of these compounds, with an emphasis on their pharmacological activities and overall therapeutic potential.
Skills
Dr. Ajoy Kumar Bauri possesses an extensive skill set that enables him to carry out advanced research in the field of bioactive natural products. His technical skills include proficiency in chromatographic techniques such as column chromatography, high-performance liquid chromatography (HPLC), and thin-layer chromatography (TLC), which he uses to isolate bioactive compounds. He is highly skilled in spectroscopic methods such as one-dimensional and two-dimensional NMR, mass spectrometry, infrared spectroscopy, and single-crystal X-ray diffraction, allowing him to accurately characterize the structure of isolated compounds. Additionally, Dr. Bauri has expertise in testing the pharmacological properties of natural products, including anti-cancer, anti-ulcer, anti-inflammatory, and anti-microbial activities. His ability to explore biosynthesis and biotransformation pathways using microbial cultures adds depth to his research, contributing to the creation of novel drug analogues. His comprehensive approach to natural product chemistry, coupled with his biomedical focus, ensures the applicability of his research in pharmaceutical development.
Conclusion
Exhibition of Förster resonance energy transfer from CdSe/ZnS quantum dot to zinc porphyrazine studied in solution.
J. Mol. Liq., 276, 770-778 (2019)
Year: 2019
Author: Ajoy Bauri
Analysis of Chemical constituents of Steam Distillate of Trachyspermum roxburghianum
Am. J. Food Sci. & Nutrition, 5(4), 76-81 (2018)
Year: 2018
Author: Ajoy Bauri
Anti-proliferative Active Flavones from the Methanol Extract of Indian Herb Artemisia reticulata.
Am. J. Pharma & Pharmacol. 5(4), 27-32 (2018)
Year: 2018
Author: Ajoy Bauri
Anti-proliferative Allyl phenol from the Methanol Extract of Piper betle.
Am. J. Pharma & Pharmacol. 5(3), 13-18 (2018)
Year: 2018
Author: Ajoy Bauri
Molecular assembly of PC70BM with a designed monoporhyrin: Spectroscopic investigation in solution and theoretical calculations.
J. Mol. Liq., 272, 137-150 (2018)
Year: 2018
Author: Ajoy Bauri
Study of Chemical Physics on Energy Transfer Phenomenon between Quantum Dots and Designed Diporphyrin in Solution.
J. Mol. Liq., 263, 64-71 (2018)
Year: 2018
Author: Ajoy Bauri
Synthesis and Evaluation of Polyphenolic Malabaricones for their Anti-cancer Potential.
BARC NEWSLETTER Research Article, September-October 2018
Year: 2018
Author: Ajoy Bauri
The spice-derived phenolic, malabaricone B induces mitochondrial damage in A549 cells via p53-independent pathway.
Food & Function, 14:9(11), 5715-5727 (2018)
Year: 2018
Author: Ajoy Bauri
Crystal structure of tetrahydro seselin, an angular pyranocoumarin.
Acta Cryst. E, 2017-06-21
Year: 2017
DOI: 10.1107/S205698901700932X
Author: Ajoy Bauri
(10R,13R)-17-(6-Hydroxy-5-methylheptan-2-yl)10,13-dimethyl-2,3,4,7,10,11,12,13,14,15,16,17,-tetradecahydro-1H cyclopenta[a] phenanthre-3-ol hemihydrate: a bioactive steroid isolated from the Indian herb Artemisia reticulata.
Year: 2017
Author: Ajoy Bauri
Crystal structure of a photobiologically active brominated angular pyranocoumarin: bromo hydroxyl seselin.
Acta Cryst (2017). E73, 453-455
Year: 2017
Author: Ajoy Bauri
Crystal structure of dibromomethoxy seselin, a photobiologically active pyranocoumarin.
Acta Cryst (2017). E73, 774-776
Year: 2017
Author: Ajoy Bauri
Crystal structure of tetrahydro seselin, an angular pyranocoumarin.
Acta Cryst (2017). E73, 1117-1120
Year: 2017
Author: Ajoy Bauri
Identification of GTP binding nuclear protein Ran as an upregulation target in acetoin glycoside mediated plant growth enhancement.
Natural Product Journals, 7, 1-7 (2017)
Year: 2017
Author: Ajoy Bauri
Crystal structure of Bergapten, a photomutagenic and photobiologically active furanocoumarin.
Acta Cryst. E, 2016-07
Year: 2016
Author: Ajoy Bauri
Crystal structure of bergapten: a photomutagenic and photobiologically active furanocoumarin.
Cryst. Acta. E72, 1194-1196 (2016)
Year: 2016
Author: Ajoy Bauri