Stefano Ratti | Biology and Life Sciences | Innovative Research Award

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Innovative Research Award

Stefano Ratti

Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum – University of Bologna, Italy

Stefano Ratti
Affiliation Alma Mater Studiorum – University of Bologna
Country Italy
Scopus ID 57045495800
Documents 132
Citations 2,250
h-index 27
Subject Area Biology and Life Sciences
Event Top Teachers Awards
ORCID 0000-0002-6258-5345

Stefano Ratti, M.D., Ph.D. is a Full Professor of Human Anatomy at the Alma Mater Studiorum – University of Bologna, Italy. His academic career combines expertise in human anatomy, molecular and cellular signalling, translational medicine, neuro-oncology, rare diseases, cardiovascular biology, and innovative medical education. As Principal Investigator of the Cellular Signalling Laboratory and curator of the Luigi Cattaneo Anatomical Waxes Collection, he has contributed to both scientific advancement and educational innovation through interdisciplinary research, international collaborations, and scholarly dissemination.[1]

Abstract

This article presents an academic overview of Stefano Ratti and evaluates the significance of his scientific, educational, and institutional contributions within the fields of anatomy, molecular medicine, cellular signalling, and biomedical innovation. His research has focused on phosphatidylinositol-dependent signalling pathways, rare diseases, glioblastoma, cardiovascular disorders, precision medicine, and advanced anatomical education. Through leadership of multidisciplinary projects, editorial service, international collaborations, and scholarly publications, he has established a research profile characterized by translational relevance and educational impact.[1][2]

Keywords

Human Anatomy, Cellular Signalling, Molecular Medicine, Glioblastoma, Rare Diseases, Precision Medicine, Medical Education, Graphic Medicine, Body Donation to Science, Neuro-oncology, Biomedical Innovation, Translational Research.

Introduction

Professor Stefano Ratti completed his Medical Degree with honors at the University of Bologna in 2016 and subsequently earned a Ph.D. in Biomedical and NeuroMotor Sciences in 2019. His doctoral work investigated the translational relevance of phospholipase C β-dependent signalling in myelodysplastic syndromes, laying the foundation for a research trajectory centered on intracellular signalling pathways and disease mechanisms. His academic progression includes research fellowships, international training experiences, associate professorship, and appointment as Full Professor of Human Anatomy in 2023.[1]

His scientific activities span hematologic disorders, gastrointestinal diseases, neurodegenerative conditions, glioblastoma, and cardiovascular pathology. Alongside laboratory investigations, he has contributed to anatomical science through research on surgical anatomy, augmented reality, robotics, minimally invasive techniques, and innovative teaching methodologies.[2]

Research Profile

Professor Stefano Ratti serves as Principal Investigator of the Cellular Signalling Laboratory at the Department of Biomedical and Neuromotor Sciences. His investigations focus on nuclear phosphoinositide signalling, molecular topography, rare disease mechanisms, neuro-oncology, cardiac biology, and translational medicine. Research programs under his leadership integrate cellular models, tissue analysis, advanced imaging, and clinical collaborations to improve understanding of disease progression and therapeutic opportunities.[1]

  • Full Professor of Human Anatomy, University of Bologna.
  • Principal Investigator of the Cellular Signalling Laboratory.
  • Scientific Curator of the Luigi Cattaneo Anatomical Waxes Collection.
  • President of Graphic Medicine Italia.
  • President-elect of the Italian Society of Histochemistry (2026–2029).
  • Author of 132 Scopus-indexed publications.

Research Contributions

Professor Stefano Ratti’s contributions encompass molecular biology, anatomical sciences, translational medicine, and educational innovation. His work has clarified the role of phosphatidylinositol signalling networks in rare diseases and cancer, particularly within myelodysplastic syndromes, glioblastoma, autosomal dominant leukodystrophy, chronic intestinal pseudo-obstruction, and cardiac amyloidosis.[3]

Beyond molecular research, he has promoted anatomical innovation through body donation programs, three-dimensional endoscopic approaches, augmented reality applications, robotics-assisted training, and graphic medicine methodologies. These initiatives seek to enhance both medical education and clinical training by integrating emerging technologies with anatomical science.[4][5]

  • Investigation of nuclear phosphoinositide signalling pathways.
  • Research on glioblastoma and neuro-oncological mechanisms.
  • Studies on rare neurological and gastrointestinal disorders.
  • Development of body-donor-based precision medicine platforms.
  • Advancement of graphic medicine and anatomy education.
  • International collaboration with institutions in Italy, the United Kingdom, the United States, and South Korea.

Publications

Among Professor Stefano Ratti’s most significant publications are studies on chronic intestinal pseudo-obstruction, glioblastoma susceptibility, body donation to science, and graphic medicine, highlighting advances in translational medicine, anatomy education, neuro-oncology, and rare disease research.

Professor Stefano Ratti has authored more than one hundred peer-reviewed scientific publications and numerous educational texts. Representative recent publications illustrate the diversity of his research interests, ranging from molecular pathology and neurodegeneration to anatomy education and biomedical communication.[2][3][4][5]

Research Impact

The scholarly influence of Professor Stefano Ratti is reflected in a publication record comprising 132 indexed documents, approximately 2,250 citations, and an h-index of 27. His research has contributed to improved understanding of disease mechanisms and fostered translational pathways linking laboratory discoveries with clinical practice. Through funded projects, editorial leadership, and international partnerships, he has strengthened interdisciplinary research networks across Europe, North America, and Asia.[1][2]

His educational contributions include authorship of anatomy textbooks, adaptation of major international anatomical references, development of graphic medicine resources, and implementation of technology-enhanced teaching methods. These activities have expanded access to anatomy education while supporting innovation in medical training.[5]

Award Suitability

Professor Stefano Ratti demonstrates a profile aligned with the objectives of the Innovative Research Award through sustained scientific productivity, leadership in biomedical research, educational innovation, and institutional service. His work integrates anatomy, molecular biology, precision medicine, and technological advancement while maintaining a strong commitment to public engagement and interdisciplinary collaboration.[1]

Notable distinctions include the Ferraguti Award for neuro-oncology research, recognition as Best Researcher Under 40 by the Italian Society of Anatomy and Histology, multiple international grants and fellowships, leadership of competitive research projects, and extensive editorial responsibilities. These achievements collectively demonstrate broad contributions to scientific knowledge and academic development.[2]

Conclusion

Stefano Ratti represents a multidisciplinary academic whose contributions bridge human anatomy, molecular medicine, translational science, and educational innovation. His research portfolio, international collaborations, leadership positions, publication record, and commitment to advancing biomedical education provide a strong foundation for recognition within academic and scientific award programs. The combination of scholarly achievement, societal engagement, and institutional leadership supports consideration for distinction within the framework of the Top Teachers Awards and the Innovative Research Award initiative.[1][2]

References

  1. Elsevier. (n.d.). Scopus author details: Stefano Ratti, Author ID 57045495800. Scopus. https://www.scopus.com/authid/detail.uri?authorId=57045495800
  2. Alma Mater Studiorum – University of Bologna. (n.d.). Curriculum Vitae and Academic Profile of Stefano Ratti. https://www.unibo.it/sitoweb/stefano.ratti/cv-en
  3. Boschetti E., Ratti S., et al. (2026). Collagen and microvascular alterations contribute to neuromuscular degeneration and disease progression in chronic intestinal pseudo-obstruction. Journal of Internal Medicine. DOI: https://doi.org/10.1111/joim.70078
  4. Fazio A., Vara G., Ratti S., et al. Medical students’ perspectives on body donation to science within the Italian context. Anatomical Sciences Education. DOI: https://doi.org/10.1002/ase.70295
  5. Moretti V., Baraldi E., Burra P., Ratti S. From comics to care: exploring the education potential of graphic novels in organ transplantation. Medical Humanities. https://mh.bmj.com/content/52/2/216

Zhi-Hui Zhu | Biology | Research Excellence Award

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Dr. Zhi-Hui Zhu | Biology | Research Excellence Award

College of Animal Science, Zhejiang University | China

Dr. Zhi-Hui Zhu is a dedicated life sciences researcher with strong expertise in molecular biology, cell biology, and genetic developmental biology, with a focus on zebrafish models for studying liver development, regeneration, and disease mechanisms. His research significantly advances understanding of nucleolar stress, macromolecular phase separation, and gene regulation in cellular stress responses and cancer biology. He has also contributed to innovative drug discovery efforts targeting complex diseases such as cancer and Alzheimer’s disease. With a solid publication record indexed in Scopus (71 citations, 4 documents, h-index 3), his work reflects impactful contributions to biomedical science. His multidisciplinary approach integrates functional genomics and experimental biology to address critical challenges in human health.

Citation Metrics (Scopus)

100
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40
20
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Citations
71

h-index
3

Documents
4

Citations

h-index

Documents

Featured Publications

Tom Mammone | Biology | Best Researcher Award

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Dr.Tom Mammone | Biology | Best Researcher Award

Senior Research Scientist at Estee. Lauder, United States.

Thomas Mammone is a distinguished researcher in dermatology and skin biology, with extensive contributions to understanding cellular responses to environmental stressors. His work has significantly advanced knowledge of oxidative stress, DNA repair, and protective mechanisms against UV radiation. Mammone has collaborated with leading scientists in dermatological research, focusing on novel skincare and therapeutic applications. His publications cover a broad spectrum of topics, from the effects of green tea phenols on UVB-induced DNA damage to the role of histamine receptors in sebocytes. With a deep interest in cellular aging, inflammation, and protective biomolecules, he has contributed to groundbreaking skincare formulations. His extensive experience in laboratory research, coupled with expertise in experimental dermatology, has positioned him as a leader in the field. Throughout his career, Mammone has worked with prestigious institutions, co-authoring numerous peer-reviewed articles that continue to influence dermatological science. His work remains a cornerstone of modern skin research.

professional profiles📖

Scopus

Education 🎓

Thomas Mammone earned his academic credentials in biological sciences and dermatology-related research from renowned institutions. His foundational studies focused on cellular biology, molecular mechanisms of skin aging, and oxidative stress responses. He pursued advanced education in biochemistry, skin pharmacology, and immunology, which laid the groundwork for his extensive research on epidermal keratinocytes, fibroblasts, and antioxidant mechanisms. Through his academic training, Mammone developed expertise in dermatological cell biology, investigating key pathways in inflammation, DNA repair, and skin barrier function. His education provided a strong background in experimental techniques, allowing him to explore how environmental stressors like UV radiation impact skin cells. With a firm grasp of biochemical pathways, his studies emphasized translational research, bridging the gap between laboratory findings and real-world dermatological applications. His educational journey has been instrumental in shaping his research focus on developing innovative skincare solutions and therapeutic interventions.

work Experience💼

Thomas Mammone has accumulated vast experience in dermatological research, focusing on cellular responses to environmental stressors, oxidative damage, and skin protection. He has held research positions in renowned laboratories, contributing to groundbreaking studies on UV protection, inflammation modulation, and DNA repair enhancement. His expertise spans in vitro and in vivo experimental dermatology, employing advanced techniques to investigate keratinocyte and fibroblast behavior under stress conditions. Throughout his career, Mammone has worked in both academic and corporate research settings, bridging scientific discoveries with skincare innovations. He has collaborated with interdisciplinary teams, integrating dermatological science with cosmetic formulations. His work has led to the development of novel skincare solutions that enhance cellular protection against environmental damage. With an extensive portfolio of peer-reviewed publications, he has established himself as a leader in the field of dermatological cell biology, continuously pushing the boundaries of skin research and therapeutic advancements.

Research Focus

Thomas Mammone’s research focuses on skin biology, cellular responses to environmental stressors, and innovative dermatological interventions. His work explores the mechanisms of oxidative stress, inflammation, and DNA damage repair in keratinocytes and fibroblasts. He has conducted extensive studies on the effects of UV radiation on human skin, examining protective strategies such as antioxidants, DNA repair enzymes, and novel pharmacological agents. His research also investigates the role of histamine receptors, osmotic stress responses, and apoptosis in skin aging and pathology. Mammone is particularly interested in developing cosmeceutical formulations that enhance skin protection and rejuvenation. His work integrates molecular biology, pharmacology, and dermatology, providing a comprehensive understanding of skin defense mechanisms. By bridging fundamental science with practical applications, his research has led to groundbreaking skincare innovations that improve skin resilience against environmental damage, making significant contributions to both scientific knowledge and consumer skincare solutions.

Awards & Honors🏆 

Thomas Mammone has received multiple recognitions for his contributions to dermatological research, particularly in the areas of oxidative stress, DNA repair, and UV protection. His work on cellular responses to environmental stressors has been honored by prestigious scientific organizations. Mammone has been invited as a keynote speaker at dermatology and skincare conferences worldwide, highlighting his expertise in skin biology and inflammation modulation. His research on antioxidants in skincare has earned industry accolades, leading to commercial applications in cosmeceuticals. He has also been recognized for his collaborative efforts with renowned scientists in dermatological research. His pioneering studies on the protective effects of salicylic acid, green tea phenols, and DNA repair enzymes in skincare have influenced modern dermatology. Mammone’s dedication to scientific excellence and translational research has positioned him as a thought leader in skin health, earning him accolades from both academic and industry professionals.

Conclusion✅

Dr. Thomas Mammone has an impressive research history in dermatology, cosmetic science, and oxidative stress. His contributions to skin protection, cellular stress response, and DNA repair mechanisms make him a strong candidate for the Best Researcher Award. However, the lack of recent high-impact publications and leadership roles slightly weakens his nomination. If he has continued research activity post-2010 with relevant advancements, he would be a top contender for the award.

Publications to Noted 📚

Self-assembly of short biopeptides onto skin tissue components studied using QCM-D

Authors: N.S. Murthy, N. Sanjeeva, E. Tavasoli, Elham, T. Mammone, Thomas, N. Karaman-Jurukovska, Nevena

Journal: International Journal of Cosmetic Science

Year: 2025

Citations: 0

Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits

Authors: C. Ligorio, Cosimo, E. Tavasoli, Elham, N. Karaman-Jurukovska, Nevena, T. Mammone, Thomas, Á. Mata, Álvaro

Journal: ACS Applied Bio Materials

Year: 2025

Citations: 0

S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis

Authors: Y. Niki, Yoko, N. Adachi, Naoko, M. Fukata, Masaki, N. Saito, Naoaki, T. Ueyama, Takehiko

Journal: Journal of Investigative Dermatology

Year: 2023

Citations: 10

Post-Inflammatory Hyperpigmentation in Dark Skin: Molecular Mechanism and Skincare Implications

Authors: E. Markiewicz, Ewa, N. Karaman-Jurukovska, Nevena, T. Mammone, Thomas, O.C. Idowu, Olusola Clement

Journal: [No source information available]

Year: [Unknown]

Citations: 32

FRANCESCO PADUANO | Biology | Lifetime achievement Award

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Dr.FRANCESCOPADUANO|Biology|Lifetime achievement Award

RESEARCHER at MARRELLI HEALTH SRL, Italy.

Dr. Francesco Paduano is the Head of Medical and Molecular Genetics at MARRELLI HEALTH SRL and a researcher at TECNOLOGICA RESEARCH INSTITUTE in Crotone, Italy.He earned his PhD in Molecular Oncology, Experimental Immunology, and Development of Innovative Therapies from the University “Magna Graecia” of Catanzaro in 2012 and completed his specialization in Medical Genetics with highest honors from the same institution in 2022.Dr. Paduano holds five National Scientific Qualifications in fields including Biochemistry, Applied Biology, and Health Sciences.His research focuses on medical genetics, stem cell biology, and cancer research, leading to 58 peer-reviewed articles, four book chapters, and two patents.He serves as a Review Editor for journals such as Frontiers in Cell and Developmental Biology and Genes, and has received multiple awards, including the international GIANNI BONADONNA Prize for new drugs in oncology.

professional profiles📖

Education 🎓

Specialization in Medical Genetics (2022) – University Magna Græcia of Catanzaro, 70/70 cum laude.PhD in Molecular Oncology, Experimental Immunology & Innovative Therapies (2012) – University Magna Græcia of Catanzaro.State Exam for Biologist Profession (2010) – University of Calabria.Master in Bioinformatics (2006) – University of Milano-Bicocca.Bachelor’s Degree in Biological Sciences (Biomolecular Pathway) (2003) – University of Calabria, 110/110.Scientific High School Diploma (1995) – Liceo Scientifico E. Majorana, Cetraro.

work Experience💼

Head of Medical and Molecular Genetics Section at Marrelli Health SRL (2022–present).Researcher at University of Naples Federico II (2023) – Conducted genetic analyses for postnatal molecular diagnostics in osteogenesis imperfecta.Senior Researcher at Calabrodental S.R.L. (2015–present).Researcher in Oncological and Regenerative Medicine Projects at institutions such as the Italian National Institute for Cancer Research and University Magna Græcia.

Research Focus

Genetic predisposition to hereditary cancers, focusing on BRCA1, BRCA2, TP53.Development of bioactive prostheses and regenerative medicine applications.Analysis of genetic variants in rare diseases.Stem cell research in dental and orthopedic applications.Oncological research, including the role of PTPRJ as a tumor suppressor.

Skills

Next Generation Sequencing (NGS) for genomic panels.Bioinformatics for molecular diagnostics.Cell culture techniques, including 3D organoids.Genetic analysis and molecular diagnostics for rare diseases.Western Blot, PCR, qPCR, and gene expression analysis.Development of biomedical devices and biomaterials.Apoptosis and cell proliferation assays for drug testin.

Awards & Recognitions

Gianni Bonadonna Prize for new drugs in oncology (2013).SIE National Award (2017) for research in endodontic regeneration.Senior Robert Frank Award (2017) for stem cell research in neurodegenerative diseases.TAOBUK da Vinci Award (2022) for innovations in predictive medicine for Parkinson’s disease.

📚Publications to Noted

  • Tatullo, M., Marrelli, M., & Paduano, F. (2015). The regenerative medicine in oral and maxillofacial surgery: the most important innovations in the clinical application of mesenchymal stem cells. International Journal of Medical Sciences, 12(1), 72-77.

  • Paduano, F., Marrelli, M., White, L. J., Shakesheff, K. M., & Tatullo, M. (2016). Odontogenic differentiation of human dental pulp stem cells on hydrogel scaffolds derived from decellularized bone extracellular matrix and collagen type I. PLOS One, 11(2), e0148225.

  • Caruana, A., Savina, D., Macedo, J. P., & Soares, S. C. (2019). From platelet-rich plasma to advanced platelet-rich fibrin: biological achievements and clinical advances in modern surgery. European Journal of Dentistry, 13(2), 280-286.

  • Folini, M., Brambilla, C., Villa, R., Gandellini, P., Vignati, S., Paduano, F., … & Zaffaroni, N. (2005). Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells. European Journal of Cancer, 41(4), 624-634.

  • Marrelli, M., Paduano, F., & Tatullo, M. (2013). Cells isolated from human periapical cysts express mesenchymal stem cell-like properties. International Journal of Biological Sciences, 9(10), 1070-1078.

  • Marrelli, M., Codispoti, B., Shelton, R. M., Scheven, B. A., Cooper, P. R., Tatullo, M., & Paduano, F. (2018). Dental pulp stem cell mechanoresponsiveness: effects of mechanical stimuli on dental pulp stem cell behavior. Frontiers in Physiology, 9, 1685.

  • Paduano, F., Marrelli, M., Amantea, M., Rengo, C., Rengo, S., Goldberg, M., & Tatullo, M. (2017). Adipose tissue as a strategic source of mesenchymal stem cells in bone regeneration: a topical review on the most promising craniomaxillofacial applications. International Journal of Molecular Sciences, 18(10), 2140.

  • Paduano, F., Villa, R., Pennati, M., Folini, M., Binda, M., Daidone, M. G., & Zaffaroni, N. (2006). Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in prostate cancer cells. Molecular Cancer Therapeutics, 5(1), 179-186.

  • Conclusion

    Based on his exceptional research, technological contributions, and academic impact, Dr. Paduano is highly suitable for a Lifetime Achievement Award in Medical Research and Biotechnology. His work in oncology, genetics, and regenerative medicine has significantly shaped the field, making him a deserving candidate for this prestigious recognition.